Use of spray drying for small scale sample preparation of Amorphous Solid Dispersion Intermediates (by Mark Saunders)

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Rudy Visbeek is a Director at ProCepT and mrf Inco, a Spanish subsidiary of ProCepT offering process and engineering services. Besides his know-how in mechanics and automation he has built up expertise in Thermodynamics of the ProCepT drying technologies: vacuum, microwaves, fluid bed, coating, spray drying. Rudy is involved in several consulting projects to optimize production drying processes. Rudy has a Master in Electro Mechanical Engineering.

Filip Van der Gucht is a Director at ProCepT managing the Sales & Marketing and Develops the last years the contract Service market in process feasibility for ProCepT. Filip has built up 20 years hands-on process know-how in drying/agglomeration/coating technologies since the start of ProCepT and is involved in several contract development and scale-up projects for third parties. Filip focused the last years on Spray Drying, processed more than 200 compounds and supervised 3 Master proofs in this field:
• Optimization of a Micro-Spray dryer by investigating the influence of nozzles, cyclones and process variables on the particle size and on the powder quality
• Spray Drying process optimization of a PLGA/API solid dispersion
• Spray Drying scale-up from mg to kg scale
Filip has a Master in Chemical Engineering Bio Technology

Filipe Gaspar is a Chemical Engineer (with a degree from Technical University of Lisbon) and a PhD from University of Birmingham (UK). After receiving his PhD he worked as a Research Fellow at the University of Birmingham and as a consultant in the field of supercritical fluids. He joined Hovione in 2003 and participated in the commissioning of the first large scale spray dryer. In 2004 he integrated the R&D group and two years later become the Director of the Particle Design Discipline. Since then, his work includes the application of solubilization platforms and novel particle size reduction technologies. His areas of interest include i) Particle Engineering technologies ii) Quality by Design and iii) Lean Manufacturing.

Maria Flores is an Organic Chemistry (with a degree from UAH) and a PhD from Universidad Autónoma de Madrid (Spain). Since her PhD on inositolphosphogycans as insulin second messengers, she has been working in Medicinal Chemistry including Chemical Synthesis, Structure Activity Relationships and Molecules of Biological Interest. She joined PharmaMar in 2001 to continue working with Active Molecules, marine compounds with cytostatic activity. In 2004 she moved to Seville and joined Ingeniatrics becoming the Director of Research and Development. Ingeniatrics’ R&D Department is focused on the development of microencapsulation applications of own proprietary technologies Flow Focusing® and Flow Blurring®. Main sectors of interest are Pharma, Food and Biotech industries.

Mark was awarded his first degree in Biological and Medicinal Chemistry from the University of Exeter and his PhD in Pharmaceutical Drug Delivery from the London School of Pharmacy. After finishing his PhD, Mark worked for the London based legal firm SJ Berwin, providing analytical testing in support of a successful major patent litigation trial. After this, Mark was appointed Physical Scientist at a small London based Contract Research Organisation (CRO) where he oversaw the growth and development of the company through to a commercial sell in 2007. Recently, Mark was involved in the commercial set up of Kuecept Ltd, a specialist drug delivery company focussing on early phase product development of poorly soluble compounds. Mark is a member of the UK and US Controlled Release Societies, Royal Society of Chemistry, Association of Pharmaceutical Scientists (APS) and UK Thermal Methods Group and sits on the committee of the APSGB Materials Science Focus Group