Mi-Pro Granulator Vacuum Dryer

The ProCepT Mi-Pro combines high shear wet/melt granulation and vacuum drying in a single pot process.

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Set-up

The granulator is used to create wet agglomerates by high shear wet mixing of different powders. The atomizing nozzle sprays the solvent with binder or active on the powder vortex, created by the impeller and chopper. The Mi-Pro features:

Combination of plexi and glass for excellent process transparency
Monitoring and control of all critical parameters
Stainless steel vessels available
Water and organic solvents
Easy clean-ability and strip-down of components in minutes
Different vessel and motor sizes (for scale up)
Quick changeover
Unit can be used for pre-clinical and clinical applications

Typical applications

Wet granulation

The wet granulation process is one of the most common ways to granulate. A liquid solution/suspension is added to a mix of dry powders to form an agglomerated more dense mass, ultimately resulting in the formation of free flowable granules or pellets.

API loading

An API loading solution is atomized on a carrier, being homogeneously mixed, in order to load the carrier with API. After atomization, vacuum is applied to remove the solvent.

Melt granulation

Melt agglomeration is a process by which the solid fine particles are bound together into agglomerates, by agitation, kneading and layering, in the presence of a molten binding liquid. Dry agglomerates are obtained as the molten binding liquid solidifies by cooling.

Vacuum Drying

This option is ideal for high toxic applications, allowing granulation and drying in one system.

Modularity

The flexible set-up with granulator module positioned on a bench-top and control unit next to it, allows you to easily connect the Excel Control of other process modules. The Mi-Pro is also available as complete stand-alone system.

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