High Shear Granulator

The ProCepT Granulator is used for wet or melt high shear granulation and pelletisation. Depending on vessel size, the typical batch range varies from 15g to 1kg of product.

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Set-up

The granulator is used to create wet agglomerates by high shear wet mixing of different powders. The atomized nozzle sprays the solvent with binder or active on the powder vortex, created by the impeller and chopper. The ProCepT Granulator is the ideal equipment for formulation R&D, demonstration or educational purposes and features:

Combination of plexi and glass for excellent process transparency
Stainless steel vessels available
Integrated on a trolley, wall mounted or on a fixed table/floor stand
Monitoring and control of all critical parameters
Water and organic solvents
Easy clean-ability and strip-down of components in minutes
Different vessel sizes (for scale-up)
Atomization nozzle with different orifices
Quick changeover
Critical process data such as temperatures, pressures and speeds are handled by the control unit
Unit can be used for pre-clinical and clinical applications

Typical applications

Wet granulation

The wet granulation process is one of the most common ways to granulate. A liquid solution/suspension is added to a mix of dry powders to form an agglomerated more dense mass, ultimately resulting in the formation of free flowable granules or pellets.

Melt granulation

Melt agglomeration is a process by which the solid fine particles are bound together into agglomerates, by agitation, kneading and layering, in the presence of a molten binding liquid. Dry agglomerates are obtained as the molten binding liquid solidifies by cooling.

Modularity

ProCepT’s modular design allows us to provide full flexibility towards integrating the equipment in your laboratory. Various set-ups or even customized designs are possible. The Excel Control system and fanbox can be combined with other ProCepT process modules (such as Pan Coater, Spray Dryer or Granulator) to save lab space and total investment costs. Extra processes can easily be added at a later point in time for a phased investment.